Parkinson’s disease treatment Decision Support System

The medication change model, which was developed in collaboration with medical experts, using a qualitative multi-criteria method, identifies situations in which the disease has progressed to the point which requires a change of medical therapy and then suggests what kind of changes should be made. GATEKEEPER KETs such as wearable sensors to continuously or periodically measure motor symptoms (depending on disease severity) and digital applications, such as Smart TVs, that can be used to detect non-motor symptoms are used to record data into the patient’s EHR, accessible in the GK Healthcare Space. The model will alert clinicians that the patient’s current medication plan is not optimal any more, and will derive suggestions on how to improve it.

Target population:

Up to 100 PD patients, with confirmed PD diagnosis according to Movement Disorders Society Clinical Diagnostic Criteria for Parkinson’s Disease; moderate PD clinical stage: moderate motor symptoms, limitations in Activities of Daily living but somewhat independent and good response to conventional pharmacologic therapy.

Key enabling technologies:

  • STAT-ON Parkinson’s Holter (Sense4care). 
  • Devices/wearables to measure blood pressure and sleep patterns. 
  • Cognitive, behavioural and mood screening app including the following validated tests and questionnaires: MoCA test,  QUIP-RS questionnaire, PsycH-Q questionnaire, LARS questionnaire, and GDS test. 
  • Professional’s online platform/dashboard, providing overview of alarm signs and/or relevant information.